Statistics

This is a first ana­lys­is on doc­u­mented cases of the LEOSS study on the epi­demi­ology of SARS-CoV­‑2.

More than 20 research teams work­ing on com­pre­hens­ive ana­lyses using the LEOSS data. A pub­lic data set is now avail­able. All sci­ent­ists are invited to register to get access to the more extens­ive sci­entif­ic data set.

Note, in the fol­low­ing dia­grams, we present descript­ive ana­lys­is. This means, in the graphs, the dis­tri­bu­tion of val­ues is pic­tured for each clin­ic­al phase sep­ar­ately. The data of one patient is e.g. included in the dis­tri­bu­tion for the uncom­plic­ated phase AND the com­plic­ated phase. A cause-effect ana­lys­is is not yet per­formed.

With a click on each image you can open a lar­ger ver­sion.


Study Population

statistics gender

Definition of Clinical Phases & Distribution at Diagnosis

Uncomplicated Phase

asymto­mat­ic

OR

symp­toms of upper res­pir­at­ory tract infec­tion

naus­ea, emes­is, diarrhea

fever

Complicated Phase

need for new oxy­gen sup­ple­ment­a­tion

clin­ic­ally mean­ing­ful increase of pri­or oxy­gen home ther­apy

PaO2 at room air < 70 mmHg

SO2 at room air < 90 %

AST or ALT > 5x ULN

new car­di­ac arrhythmia

new peri­car­di­al effu­sion > 1 cm

new heart fail­ure with pul­mon­ary edema, con­gest­ive hep­ato­pathy or peri­pher­al edema

Critical Phase

need for cat­echolam­ines

life-threat­en­ing car­di­ac arrhythmia

need for unplanned mech­an­ic­al vent­il­a­tion (invas­ive or non-invas­ive)

pro­long­a­tion (>24h) of planned mech­an­ic­al vent­il­a­tion

Liv­er fail­ure with Quick < 50 % or INR > 3.5

qSOFA >= 2

acute ren­al fail­ure in need of dia­lys­is

Recovery Phase

improve­ment by one degree of sever­ity accord­ing to this scheme or dis­charge from hos­pit­al

AND

defer­ves­cence

AND

no fur­ther pro­gres­sion or re-hos­pit­al­iz­a­tion

statistics on stage of patient at diagnosis

Comorbidities

statistics on distribution of comorbidities
statistics on distribution of comorbidities

Please note:
We excluded cases with ongo­ing doc­u­ment­a­tion in the fol­low­ing graph­ics.


Liver Enzymes

Distribution of GOT/AST in clinical phases of SARS-COV-2 / COVID-19
Distribution of GPT/ALT in clinical phases of SARS-COV-2 / COVID-19
Distribution of Gamma-GT in clinical phases of SARS-COV-2 / COVID-19


Cardiac Markers

Distribution of  troponine T in clinical phases of SARS-COV-2 / COVID-19
Distribution of LDH in clinical phases of SARS-COV-2 / COVID-19

Distribution of  NT-pro-BNP in clinical phases of SARS-COV-2 / COVID-19
Distribution of  creatinine kinase in clinical phases of SARS-COV-2 / COVID-19

Inflammatory Markers

Distribution of CRP in clinical phases of SARS-COV-2 / COVID-19
Statistics on the distribution of ferritin levels in clinical phases of SARS-COV-2 / COVID-19
Distribution of interleukin-6 in clinical phases of SARS-COV-2 / COVID-19
Distribution of soluble interleukin-2 receptor in clinical phases of SARS-COV-2 / COVID-19

Clinical Findings

Statistics
Statistics

Scroll to top